Tieu Long Phan

Tieu Long Phan

MS. in Pharmacy; Expertise in applying machine learning techniques, cheminformatics and automated pipeline to screen new biologically active molecules.

Publications

Application of medicinal chemistry filtration and molecular docking in selecting STAT3 inhibitors from CUCURBITACIN E derivatives

Published in Vietnamese Pharmacy Journal, 2023

Cancer is one of the leading causes of death worldwide with nearly 10 million deaths recorded in 2020, according to the World Health Organization report. While targeting STAT3 (Signal transducer and activator of transcription 3) has been known as a promising pathway for controlling tumor growth, cucurbitacin is considered potential for…

Recommended citation: Tieu Long Phan, Anh Hao Huynh, Nhu Ngoc Nguyen Song, Dong Nghi Nguyen Hoang, Ngoc Tam Chan Nguyen, Ngoc Tuyen Truong (2023). Application of medicinal chemistry filtration and molecular docking in selecting STAT3 inhibitors from CUCURBITACIN E derivatives. Vietnamese Pharmacy Journal (Accepted).

Study on the effect of molecular fingerprints on the performance of machine learning model predicting hiv integrase bioactivty

Published in Vietnamese Pharmacy Journal, 2023

HIV-1 has been causing severe pandemics since the 1980s by attacking the host immune system. If HIV-1 is not treated, it can eventually lead to AIDS (acquired immunodeficiency syndrome), where death is inevitable due to opportunistic infections. Therefore, discovering new HIV-1 antiviral drugs is…

Recommended citation: Tieu Long Phan, Thanh An Pham, Bao Vy Doan Ngoc, Hoang Son Le Lai, Ngoc Tuyen Truong (2023). Study on the effect of molecular fingerprints on the performance of machine learning model predicting HIV integrase bioactivty. Vietnamese Pharmacy Journal (Accepted).

Design, synthesis, antimicrobial evaluations and in silico studies of novel pyrazol-5(4H)-one and 1H-pyrazol-5-ol derivatives

Published in Arabian Journal of Chemistry, 2022

A new series of 1,4-disubstituted 3-methylpyrazol-5(4H)-one derivatives were synthesized by reacting various substituted aromatic aldehydes with 3-methylpyrazol-5(4H)-one derivatives through Knoevenagel condensation by conventional as well as by exposure to microwave irradiations…

Recommended citation: Em, P. C., L. T. Tuong Vi, T. P. Long, T. N. Huong-Giang, N. B. L. Khanh, and N. T. Tuyen. "Design, synthesis, antimicrobial evaluations and in silico studies of novel pyrazol-5 (4H)-one and 1 H-pyrazol-5-ol derivatives." Arab. J. Chem 15 (2022): 103682. https://doi.org/10.1016/j.arabjc.2021.103682

Application of machine learning in virtual screening of HIV integrase inhibitors

Published in Vietnamese Pharmacy Journal, 2022

Applications of machine learning in drug design is an emerging and fast-growing field of research. In silico models allow the speeding up of drug discovery and developments…

Recommended citation: Tieu Long Phan, Xuan Truc Tran Dinh, The Chuong Trinh, Hoang Son Le Lai, Ngoc Tuyen Truong (2022). Application of machine learning in virtual screening of HIV integrase inhibitors - Vietnamese Pharmacy Journal, 506, 21-25.